Anticorps Polyclonal de lapin anti-CHMP4C

CHMP4C Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

Publications(1)

N° de cat : 16256-1-AP

Synonymes

hVps32-3, hVps32 3, hSnf7-3, hSnf7 3, Chromatin-modifying protein 4c

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Galerie de données de validation

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  WB analysis using 16256-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 16256-1-AP (CHMP4C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: TT cells,

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 1 publications below
• IHC: See 1 publications below

Informations sur le produit

16256-1-AP cible CHMP4C dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CHMP4C Protéine recombinante Ag9279
• Nom complet: chromatin modifying protein 4C
• Masse moléculaire calculée: 233 aa, 26 kDa
• Poids moléculaire observé: 35 kDa
• Numéro d’acquisition GenBank: BC014321
• Symbole du gène: CHMP4C
• Identification du gène (NCBI): 92421
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

CHMP4C (Charged multivesicular body protein 4c), also known as SHAX3. It is expected to be located in the cytoplasm and membrane, which is expressed in heart, spleen and kidney. CHMP4C is one of the charged multivesicular protein (CHMP), and is involved in the composition of the endosomal sorting complex required for transport III (ESCRT-III), facilitating the necessary separation of daughter cells. CHMP4C has been proposed to be involved in the progression of different carcinomas. The molecular weight of CHMP4C is 26 kDa. Phosphorylated at Ser-210 by AURKB during cytokinesis: together with ZFYVE19/ANCHR, phosphorylated CHMP4C retains abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis.

Publications

Species	Application	Title
human	WB,IHC	Heliyon; Analysis of cell death-related genes to evaluate the prognostic and immunotherapeutic value in bladder cancer; Authors - Mingde Gao

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