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Anticorps Polyclonal de lapin anti-CHMP4C

CHMP4C Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16256-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using CHMP4C Polyclonal antibody (16256-1-AP)

    WB analysis using 16256-1-AP (same clone as 16256-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 16256-1-AP (CHMP4C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16256-1-PBS in a different storage buffer formulation.

Informations sur le produit

16256-1-PBS cible CHMP4C dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène CHMP4C Protéine recombinante Ag9279
Nom complet chromatin modifying protein 4C
Masse moléculaire calculée 233 aa, 26 kDa
Poids moléculaire observé35 kDa
Numéro d’acquisition GenBankBC014321
Symbole du gène CHMP4C
Identification du gène (NCBI) 92421
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CHMP4C (Charged multivesicular body protein 4c), also known as SHAX3. It is expected to be located in the cytoplasm and membrane, which is expressed in heart, spleen and kidney. CHMP4C is one of the charged multivesicular protein (CHMP), and is involved in the composition of the endosomal sorting complex required for transport III (ESCRT-III), facilitating the necessary separation of daughter cells. CHMP4C has been proposed to be involved in the progression of different carcinomas. The molecular weight of CHMP4C is 26 kDa. Phosphorylated at Ser-210 by AURKB during cytokinesis: together with ZFYVE19/ANCHR, phosphorylated CHMP4C retains abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis.

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