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Anticorps Polyclonal de lapin anti-CHRNA4

CHRNA4 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21939-1-PBS

Synonymes

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using CHRNA4 Polyclonal antibody (21939-1-AP)

    WB analysis using 21939-1-AP (same clone as 21939-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21939-1-AP (CHRNA4 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21939-1-PBS in a different storage buffer formulation.

Informations sur le produit

21939-1-PBS cible CHRNA4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène CHRNA4 Protéine recombinante Ag16584
Nom complet cholinergic receptor, nicotinic, alpha 4
Masse moléculaire calculée 627 aa, 70 kDa
Poids moléculaire observé69 kDa
Numéro d’acquisition GenBankBC096290
Symbole du gène CHRNA4
Identification du gène (NCBI) 1137
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1.

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