Anticorps Monoclonal anti-CHRNA5

• Phare
• Validé par KD/KO

CHRNA5 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, porc, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3G8C11

N° de cat : 66363-1-PBS

Synonymes

CHRNA5, LNCR2, NACHRA5

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Galerie de données de validation

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  WB analysis of mouse skeletal muscle using 66363-1-Ig (same clone as 66363-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 66363-1-Ig (CHRNA5 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66363-1-PBS in a different storage buffer formulation.

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  WB analysis of pig skeletal muscle using 66363-1-Ig (same clone as 66363-1-PBS)

  pig skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 66363-1-Ig (CHRNA5 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66363-1-PBS in a different storage buffer formulation.

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  WB analysis of A549 using 66363-1-Ig (same clone as 66363-1-PBS)

  A549 cells were subjected to SDS PAGE followed by western blot with 66363-1-Ig (CHRNA5 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66363-1-PBS in a different storage buffer formulation.

• 

  WB analysis of C2C12 using 66363-1-Ig (same clone as 66363-1-PBS)

  C2C12 cell were subjected to SDS PAGE followed by western blot with 66363-1-Ig (CHRNA5 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66363-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human skeletal muscle using 66363-1-Ig (same clone as 66363-1-PBS)

  human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 66363-1-Ig (CHRNA5 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66363-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human bladder using 66363-1-Ig (same clone as 66363-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 66363-1-Ig (CHRNA5 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66363-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human bladder using 66363-1-Ig (same clone as 66363-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 66363-1-Ig (CHRNA5 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66363-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach using 66363-1-Ig (same clone as 66363-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 66363-1-Ig (CHRNA5 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66363-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human stomach using 66363-1-Ig (same clone as 66363-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 66363-1-Ig (CHRNA5 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66363-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66363-1-PBS cible CHRNA5 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, souris

• Réactivité: Humain, porc, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: CHRNA5 Protéine recombinante Ag4447
• Nom complet: cholinergic receptor, nicotinic, alpha 5
• Masse moléculaire calculée: 468 aa, 53 kDa
• Poids moléculaire observé: 53 kDa
• Numéro d’acquisition GenBank: BC033639
• Symbole du gène: CHRNA5
• Identification du gène (NCBI): 1138
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Nicotinic acetylcholine receptors (nAChRs), such as CHRNA5, are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits. Variants in the CHRNA5 gene are associated with nicotine dependence and lung cancer risk.

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