Anticorps Polyclonal de lapin anti-CHRND

CHRND Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17864-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 17864-1-AP (same clone as 17864-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17864-1-AP (CHRND antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17864-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17864-1-PBS cible CHRND dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CHRND Protéine recombinante Ag12337
• Nom complet: cholinergic receptor, nicotinic, delta
• Masse moléculaire calculée: 517 aa, 59 kDa
• Numéro d’acquisition GenBank: BC093923
• Symbole du gène: CHRND
• Identification du gène (NCBI): 1144
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS).

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