Anticorps Polyclonal de lapin anti-CIB2

CIB2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32585-1-PBS

Synonymes

Calcium and integrin-binding family member 2, Kinase-interacting protein 2, KIP 2, KIP2

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Galerie de données de validation

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  WB analysis using 32585-1-AP (same clone as 32585-1-PBS)

  Mouse heart tissue lysate was subjected to SDS PAGE followed by western blot with 32585-1-AP (CIB2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32585-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32585-1-PBS cible CIB2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CIB2 Protéine recombinante Ag38508
• Nom complet: calcium and integrin binding family member 2
• Masse moléculaire calculée: 22 kDa，187aa
• Poids moléculaire observé: 39 kDa
• Numéro d’acquisition GenBank: NM_006383.3
• Symbole du gène: CIB2
• Identification du gène (NCBI): 10518
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The CIB (calcium and integrin binding) protein family has 4 members (CIB1-CIB4), each composed of 4 EF-hand Ca2+-binding motifs (PMID: 27771768). CIB2 is broadly expressed in a variety of tissues, which plays a role in sensory neurons of the ear and eye involved in the regulation of Ca2+ homeostasis (PMID: 28663585; 29084757; 29255404). Mutations of CIB2 have been associated with autosomal recessive nonsyndromic deafness 48 (DFNB48), as well as syndromic deafness in Usher syndrome, type 1J (USH1J) (PMID: 23331261). The observed molecular weight of CIB2 is 39 kDa because it can form a dimer (PMID: 30174586).

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