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Anticorps Polyclonal de lapin anti-CIR

CIR Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32928-1-PBS

Synonymes

CBF1-interacting corepressor, CIR1, Corepressor interacting with RBPJ 1, Recepin

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using CIR Polyclonal antibody (32928-1-AP)

    WB analysis using 32928-1-AP (same clone as 32928-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32928-1-AP (CIR antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32928-1-PBS in a different storage buffer formulation.

Informations sur le produit

32928-1-PBS cible CIR dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène CIR Protéine recombinante Ag38647
Nom complet CBF1 interacting corepressor
Masse moléculaire calculée52kDa，450aa
Poids moléculaire observé23 kDa
Numéro d’acquisition GenBankNM_004882.3
Symbole du gène CIR
Identification du gène (NCBI) 9541
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CIR, a protein originally identified as a CBF1-interacting protein and reported to act as a transcriptional corepressor. CIR is a member of the family of SR-related proteins and that CIR plays a role in splicing regulation. In addition to a basic lysine and acidic serine-rich (BA) domain and a zinc knuckle-like motif, CIR has an arginine/serine dipeptide repeat (RS) domain in its C terminal region. The RS domain has been reported to be present in the superfamily of SR proteins, which are involved in splicing reactions (PMID: 15652350).

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