Anticorps Recombinant de lapin anti-CLEC10A/CD301

CLEC10A/CD301 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242636A8

N° de cat : 85911-5-PBS

Synonymes

Clec10a, C-type lectin domain family 10 member A, Macrophage asialoglycoprotein-binding protein 1, Macrophage galactose/N-acetylgalactosamine-specific lectin, M-ASGP-BP-1

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Galerie de données de validation

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  WB analysis of RAW 264.7 using 85911-5-RR (same clone as 85911-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85911-5-RR (CLEC10A/CD301 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85911-5-PBS in a different storage buffer formulation.

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Informations sur le produit

85911-5-PBS cible CLEC10A/CD301 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CLEC10A/CD301 Protéine recombinante Eg2698
• Nom complet: macrophage galactose N-acetyl-galactosamine specific lectin 1
• Masse moléculaire calculée: 35 kDa
• Poids moléculaire observé: 40 kDa
• Numéro d’acquisition GenBank: NM_010796.3
• Symbole du gène: Mgl1
• Identification du gène (NCBI): 17312
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

C-type lectin domain family 10 member A (CLEC10A), also known as CD301, macrophage galactose-type C-type lectin (MGL), DC-asialoglyco protein receptor (DC-ASGP-R) or human macrophage lectin (HML), is a type II transmembrane glycoprotein having a calcium-dependent carbohydrate recognition domain (PMID: 8598452; 11919201; 11698450). CLEC10A is expressed exclusively by myeloid professional antigen-presenting cells such as immature dendritic cells (DCs) and alternatively activated macrophages (PMID: 16998493). CLEC10A is a marker for human CD1c+ DCs (cDC2) (PMID: 29755453). It functions as an endocytic receptor for glycosylated antigens (PMID: 11919201).

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