Anticorps Recombinant de lapin anti-CLEC10A/CD301

CLEC10A/CD301 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241857C11

N° de cat : 98245-1-RR

Synonymes

CLEC10A, C-type lectin domain family 10 member A, CLECSF14, CLECSF13, CD301

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Galerie de données de validation

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  FC experiment of Human immature monocyte-derived dendritic cells using 98245-1-RR

  1x10^6 Human immature monocyte-derived dendritic cells were surface stained with 0.25 ug Anti-Human CLEC10A/CD301 Rabbit Recombinant Antibody (98245-1-RR, Clone: 241857C11) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

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  Affinity and Kinetic Characterization of 98245-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98245-1-RR against Human CLEC10A/CD301 were performed. The affinity constant is below 1 pM.

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Applications testées

• Résultats positifs en cytométrie: Human immature monocyte-derived dendritic cells

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98245-1-RR cible CLEC10A/CD301 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: C-type lectin domain family 10, member A
• Masse moléculaire calculée: 316 aa, 35 kDa
• Numéro d’acquisition GenBank: BC039011
• Symbole du gène: CLEC10A
• Identification du gène (NCBI): 10462
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

C-type lectin domain family 10 member A (CLEC10A), also known as CD301, macrophage galactose-type C-type lectin (MGL), DC-asialoglyco protein receptor (DC-ASGP-R) or human macrophage lectin (HML), is a type II transmembrane glycoprotein having a calcium-dependent carbohydrate recognition domain (PMID: 8598452; 11919201; 11698450). CLEC10A is expressed exclusively by myeloid professional antigen-presenting cells such as immature dendritic cells (DCs) and alternatively activated macrophages (PMID: 16998493). CLEC10A is a marker for human CD1c+ DCs (cDC2) (PMID: 29755453). It functions as an endocytic receptor for glycosylated antigens (PMID: 11919201).

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