Anticorps Recombinant de lapin anti-CLEC10A/CD301

CLEC10A/CD301 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

FITC Plus Fluorescent Dye

CloneNo.

241857C11

N° de cat : FITC-98245

Synonymes

CLEC10A, 241857C11, CD301, CLECSF13, CLECSF14

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Galerie de données de validation

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  FC experiment of Human immature monocyte-derived dendritic cells using FITC-98245

  1x10^6 FC receptor blocked Human immature monocyte-derived dendritic cells were surface stained with 5 ul FITC Plus Anti-Human CLEC10A/CD301 Rabbit RecAb (FITC-98245, Clone: 241857C11) (red), or 5 ul FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: Human immature monocyte-derived dendritic cells

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

FITC-98245 cible CLEC10A/CD301 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CLEC10A/CD301 Protéine recombinante Eg1892
• Nom complet: C-type lectin domain family 10, member A
• Masse moléculaire calculée: 316 aa, 35 kDa
• Numéro d’acquisition GenBank: BC039011
• Symbole du gène: CLEC10A
• Identification du gène (NCBI): 10462
• Conjugaison: FITC Plus Fluorescent Dye
• Excitation/Emission maxima wavelengths: 495 nm / 524 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

C-type lectin domain family 10 member A (CLEC10A), also known as CD301, macrophage galactose-type C-type lectin (MGL), DC-asialoglyco protein receptor (DC-ASGP-R) or human macrophage lectin (HML), is a type II transmembrane glycoprotein having a calcium-dependent carbohydrate recognition domain (PMID: 8598452; 11919201; 11698450). CLEC10A is expressed exclusively by myeloid professional antigen-presenting cells such as immature dendritic cells (DCs) and alternatively activated macrophages (PMID: 16998493). CLEC10A is a marker for human CD1c+ DCs (cDC2) (PMID: 29755453). It functions as an endocytic receptor for glycosylated antigens (PMID: 11919201).

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