Anticorps Recombinant de lapin anti-CLEC12A/CD371

CLEC12A/CD371 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242620B12

N° de cat : 98357-1-RR

Synonymes

CD371, Clec12a, CLL-1, C-type lectin domain family 12 member A, C-type lectin-like molecule 1

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Galerie de données de validation

• 

  FC experiment of mouse splenocytes using 98357-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CLEC12A/CD371 Rabbit RecAb (98357-1-RR, Clone: 242620B12) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 405 Anti-Mouse CD11c (N418) Mouse IgG2a Recombinant Antibody (CL405-65602, Clone: N418) and APC Anti-Mouse CD8a (53-6.7) (APC-65069, Clone: 53-6.7). CD8+ cells were gated. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98357-1-RR cible CLEC12A/CD371 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CLEC12A/CD371 Protéine recombinante Eg2726
• Nom complet: C-type lectin domain family 12, member a
• Masse moléculaire calculée: 31 kDa
• Numéro d’acquisition GenBank: /
• Symbole du gène: Clec12a
• Identification du gène (NCBI): 232413
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

CLEC12A, also known as CD371, MICL, DCAL-2 or CLL-1, is a type II transmembrane glycoprotein and a member of the C-type lectin superfamily (PMID: 30401586). This protein, which contains a single C-type lectin-like domain and a cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM), is related to LOX-1 and Dectin-1 and is variably spliced and highly N-glycosylated (PMID: 14739280). Its ITIM sequence recruits the tyrosine phosphatases SHP-1 and SHP-2 to negatively regulate Syk signaling.

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