Anticorps Polyclonal de lapin anti-CLEC18A

CLEC18A Polyclonal Antibody for WB, IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

N° de cat : 21013-1-AP

Synonymes

MRLP2, MRCL1, MRCL, Mannose receptor-like protein 2, C-type lectin domain family 18 member A

---

Galerie de données de validation

• 

  WB analysis of HeLa using 21013-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 21013-1-AP (CLEC18A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HeLa using 21013-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 21013-1-AP (CLEC18A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  IHC staining of human kidney using 21013-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human kidney using 21013-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 40x lens).

• 

  IHC staining of human stomach using 21013-1-AP

  Immunohistochemical analysis of paraffin-embedded human stomach using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human stomach using 21013-1-AP

  Immunohistochemical analysis of paraffin-embedded human stomach using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 40x lens).

---

Applications testées

• Résultats positifs en WB: cellules HeLa,
• Résultats positifs en IHC: tissu rénal humain, tissu d'estomac humain; il est suggéré de démasquer l'antigène avec un tampon de TE buffer pH 9.0; (*) À défaut, 'le démasquage de l'antigène peut être 'effectué avec un tampon citrate pH 6,0.

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:1000
• Immunohistochimie (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

21013-1-AP cible CLEC18A dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CLEC18A Protéine recombinante Ag15237
• Nom complet: C-type lectin domain family 18, member A
• Masse moléculaire calculée: 446 aa, 50 kDa
• Poids moléculaire observé: 47-50 kDa
• Numéro d’acquisition GenBank: BC141808
• Symbole du gène: CLEC18A
• Identification du gène (NCBI): 348174
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

CLEC18A, or C-type lectin member 18A, is a protein that plays a significant role in the human immune system, particularly in the context of viral infections. CLEC18A is widely expressed, with the highest levels found in myeloid cells and the liver. It is a co-receptor for TLR3 (Toll-like receptor 3) and is involved in enhancing the host's immune response to viral infections, such as H5N1 influenza A virus (IAV). CLEC18A has been implicated in the development of mixed cryoglobulinemia (MC), an extrahepatic manifestation associated with hepatitis C virus (HCV). This antibody can recognize CLEC18A/B/C.

{{ptg:RelatedPrimaryAntibodies}}