Anticorps Polyclonal de lapin anti-CLEC18A

CLEC18A Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21013-1-PBS

Synonymes

MRLP2, MRCL1, MRCL, Mannose receptor-like protein 2, C-type lectin domain family 18 member A

---

Galerie de données de validation

• 

  WB analysis of HeLa using 21013-1-AP (same clone as 21013-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 21013-1-AP (CLEC18A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 21013-1-AP (same clone as 21013-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 21013-1-AP (CLEC18A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 21013-1-AP (same clone as 21013-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 21013-1-AP (same clone as 21013-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human stomach using 21013-1-AP (same clone as 21013-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human stomach using 21013-1-AP (same clone as 21013-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

21013-1-PBS cible CLEC18A dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CLEC18A Protéine recombinante Ag15237
• Nom complet: C-type lectin domain family 18, member A
• Masse moléculaire calculée: 446 aa, 50 kDa
• Poids moléculaire observé: 47-50 kDa
• Numéro d’acquisition GenBank: BC141808
• Symbole du gène: CLEC18A
• Identification du gène (NCBI): 348174
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CLEC18A, or C-type lectin member 18A, is a protein that plays a significant role in the human immune system, particularly in the context of viral infections. CLEC18A is widely expressed, with the highest levels found in myeloid cells and the liver. It is a co-receptor for TLR3 (Toll-like receptor 3) and is involved in enhancing the host's immune response to viral infections, such as H5N1 influenza A virus (IAV). CLEC18A has been implicated in the development of mixed cryoglobulinemia (MC), an extrahepatic manifestation associated with hepatitis C virus (HCV). This antibody can recognize CLEC18A/B/C.

{{ptg:RelatedPrimaryAntibodies}}