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Anticorps Polyclonal de lapin anti-CLEC2D

CLEC2D Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13188-1-PBS

Synonymes

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using CLEC2D Polyclonal antibody (13188-1-AP)

    WB analysis using 13188-1-AP (same clone as 13188-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13188-1-AP (CLEC2D antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13188-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of Jurkat cells using CLEC2D Polyclonal antibody (13188-1-AP)

    WB analysis of Jurkat using 13188-1-AP (same clone as 13188-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 13188-1-AP (CLEC2D antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13188-1-PBS in a different storage buffer formulation.

Informations sur le produit

13188-1-PBS cible CLEC2D dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène CLEC2D Protéine recombinante Ag3862
Nom complet C-type lectin domain family 2, member D
Masse moléculaire calculée 154 aa, 18 kDa
Poids moléculaire observé 33 kDa
Numéro d’acquisition GenBankBC019883
Symbole du gène CLEC2D
Identification du gène (NCBI) 29121
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CLEC2D (C-type lectin domain family 2 member D), also known as LLT1 (lectin-like transcript 1) or OCIL (Osteoclast inhibitory lectin), is a single-pass type II membrane protein expressed by hematopoietic cells and osteoblasts (PMID: 21930700; 14753741). Its expression was found to be tightly correlated with activation on T cells, NK cells, B cells, and DCs (PMID: 21930700). CLEC2D is a ligand for the human NKR-P1A (CD161) receptor and their interaction differentially regulates NK- and T-cell functions (PMID: 16339513, 16339512). It inhibits the formation and function of osteoclasts and modulates the release of interferon-gamma by human NK cells (PMID:14753741; 20415786).

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