Anticorps Recombinant de lapin anti-CLEC5A

CLEC5A Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251734A11

N° de cat : 86633-2-PBS

Synonymes

CLECSF5, C-type lectin domain family 5 member A, C-type lectin superfamily member 5, MDL 1, MDL1

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Galerie de données de validation

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  WB analysis using 86633-2-RR (same clone as 86633-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86633-2-RR (CLEC5A antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86633-2-PBS in a different storage buffer formulation.

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  WB analysis using 86633-2-RR (same clone as 86633-2-PBS)

  U-87 MG cells lysate was subjected to SDS PAGE followed by western blot with 86633-2-RR (CLEC5A antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86633-2-PBS in a different storage buffer formulation.

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Informations sur le produit

86633-2-PBS cible CLEC5A dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: DNA
• Nom complet: C-type lectin domain family 5, member A
• Masse moléculaire calculée: 188 aa, 22 kDa
• Poids moléculaire observé: 22 kDa
• Numéro d’acquisition GenBank: BC112099
• Symbole du gène: CLEC5A
• Identification du gène (NCBI): 23601
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

C-type lectin domain family 5 member A (CLEC5A, also known as CLECSF5 and MDL1) is a spleen tyrosine kinase (Syk)-coupled receptor abundantly expressed by monocytes, macrophages and neutrophils (PMID: 10449773). It has a pivotal function in activating multiple aspects of innate immunity against bacterial invasion (PMID: 28824166). Both in vitro and in vivo evidence supported that CLEC5A was involved in glioblastoma pathogenesis via regulation of PI3K/Akt pathway (PMID: 30834619).

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