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Anticorps Polyclonal de lapin anti-CLN5

CLN5 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24605-1-PBS

Synonymes

EC:2.3.1.-, Ceroid lipofuscinosis neuronal protein 5, BMPS, BMP synthase CLN5, Bis(monoacylglycero)phosphate synthase CLN5, secreted form

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using CLN5 Polyclonal antibody (24605-1-AP)

    WB analysis using 24605-1-AP (same clone as 24605-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 24605-1-AP (CLN5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24605-1-PBS in a different storage buffer formulation.

Informations sur le produit

24605-1-PBS cible CLN5 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène CLN5 Protéine recombinante Ag18175
Nom complet ceroid-lipofuscinosis, neuronal 5
Masse moléculaire calculée 407 aa, 46 kDa
Poids moléculaire observé48 kDa
Numéro d’acquisition GenBankBC153154
Symbole du gène CLN5
Identification du gène (NCBI) 1203
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The CLN5 (ceroid lipofuscinosis neuronal protein 5) protein is ubiquitously expressed in the majority of tissues studied and in the brain, CLN5 shows both neuronal and glial cell expression. CLN5 plays a role in maintaining an acidic environment in the lysosomes, a critical feature for a functional lysosome (PMID: 38236309). Moreover, CLN5-deficient neuronal progenitor cells showed reduced thioesterase activity, confirming the live cell function of CLN5 in setting S-depalmitoylation levels (PMID: 35427157).

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