Anticorps Polyclonal de lapin anti-CLPTM1

CLPTM1 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 15337-1-PBS

Synonymes

Putative lipid scramblase CLPTM1

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Galerie de données de validation

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  WB analysis using 15337-1-AP (same clone as 15337-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 15337-1-AP (CLPTM1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15337-1-PBS in a different storage buffer formulation.

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  IP experiment of A549 using 15337-1-AP (same clone as 15337-1-PBS)

  IP result of anti-CLPTM1 (IP:15337-1-AP, 4ug; Detection:15337-1-AP 1:300) with A549 cells lysate 1050 ug. This data was developed using the same antibody clone with 15337-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 15337-1-AP (same clone as 15337-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 15337-1-AP (CLPTM1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15337-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 15337-1-AP (same clone as 15337-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 15337-1-AP (CLPTM1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15337-1-PBS in a different storage buffer formulation.

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Informations sur le produit

15337-1-PBS cible CLPTM1 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CLPTM1 Protéine recombinante Ag7538
• Nom complet: cleft lip and palate associated transmembrane protein 1
• Masse moléculaire calculée: 62 kDa
• Poids moléculaire observé: 65-75 kDa
• Numéro d’acquisition GenBank: BC004865
• Symbole du gène: CLPTM1
• Identification du gène (NCBI): 1209
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cleft lip and palate transmembrane protein 1 (CLPTM1), a multipass transmembrane protein, was identified due to the association of a chromosomal translocation with a cleft lip and palate (PMID: 9828125). CLPTM1 regulates epileptic seizures by modulating GABAAR-mediated inhibitory synaptic transmission (PMID: 36519412). Highly expressed CLPTM1L may contribute to a poor prognosis and increase invasion, proliferation and migration of oral squamous cell carcinoma (PMID: 34586883).

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