Anticorps Recombinant de lapin anti-CLSTN3

CLSTN3 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

240865C10

N° de cat : 83931-1-PBS

Synonymes

Alc-beta, alcbeta, Alcadein-beta, Alcadein beta, Alc beta

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Galerie de données de validation

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  WB analysis using 83931-1-RR (same clone as 83931-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83931-1-RR (CLSTN3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83931-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83931-1-RR

  Biolayer interferometry (BLl) kinetic assays of 83931-1-RR against Human CLSTN3 were performed. The affinity constant is 1.51 nM.

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Informations sur le produit

83931-1-PBS cible CLSTN3 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CLSTN3 Protéine recombinante Ag14897
• Nom complet: calsyntenin 3
• Masse moléculaire calculée: 968 aa, 107 kDa
• Numéro d’acquisition GenBank: BC039075
• Symbole du gène: CLSTN3
• Identification du gène (NCBI): 9746
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Calsyntenins, also called alcadeins, are cadherin superfamily proteins first identified as synaptic proteins (PMID: 11161476; 12498782). Calsyntenins are type I transmembrane proteins with extracellular domains containing two cadherin repeats and an LNS (laminin, neurexin, sex hormone-binding globulin) domain (PMID: 24613359). Calsyntenin-3 (CLSTN3, also known as alcadein-beta) is a synapse-organizing protein that promotes the development of synapses. It is a postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation (PMID: 25352602; 24613359).

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