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Anticorps Polyclonal de lapin anti-CNDP2

CNDP2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30025-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using CNDP2 Polyclonal antibody (30025-1-AP)

    WB analysis using 30025-1-AP (same clone as 30025-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30025-1-AP (CNDP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30025-1-PBS in a different storage buffer formulation.

Informations sur le produit

30025-1-PBS cible CNDP2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène CNDP2 Protéine recombinante Ag32312
Nom complet CNDP dipeptidase 2 (metallopeptidase M20 family)
Masse moléculaire calculée 53 kDa
Poids moléculaire observé 44-53 kDa
Numéro d’acquisition GenBankBC001375
Symbole du gène CNDP2
Identification du gène (NCBI) 55748
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Carnosine dipeptidase II (CNDP2) catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. It has high dipeptidase activity toward cysteinyl glycine, an intermediate metabolite in glutathione metabolism (PubMed:19346245, PubMed:12473676). Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis (PubMed:25964343). CNDP2 has 2 isoforms with a molecular weight of 53 and 44 kDa. The isoform 1 is ubiquitously expressed with higher levels in the kidney and liver (at protein level) and expressed in peripheral blood leukocytes (PubMed:12473676). It is also expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at the protein level) (PubMed:24395568). Isoform 2 is broadly expressed in fetal tissues and expressed in the adult liver and placenta. (PMID: 17121880).

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