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Anticorps Polyclonal de lapin anti-CNGA2

CNGA2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 23823-1-PBS

Synonymes

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using CNGA2 Polyclonal antibody (23823-1-AP)

    WB analysis using 23823-1-AP (same clone as 23823-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23823-1-AP (CNGA2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23823-1-PBS in a different storage buffer formulation.

Informations sur le produit

23823-1-PBS cible CNGA2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène CNGA2 Protéine recombinante Ag19899
Nom complet cyclic nucleotide gated channel alpha 2
Masse moléculaire calculée 664 aa, 76 kDa
Poids moléculaire observé80 kDa
Numéro d’acquisition GenBankBC126302
Symbole du gène CNGA2
Identification du gène (NCBI) 1260
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purifié par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cyclic nucleotide-gated (CNG) channels are crucial for visual and olfactory transductions (PMID: 12432397). Native CNG channels are heterotetramers composed of homologous A and B subunits. The olfactory CNG channels are composed of two CNGA2 subunits, one CNGA4 and one CNGB1b subunit, each containing a cyclic nucleotide-binding domain (PMID: 22786723). CNGA2, also named as CNCA, CNCA1 and CNCG2, is the primary subunit of the olfactory CNG channel. Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. Activation of olfactory channel by cyclic nucleotides leads to a depolarization of olfactory sensory neurons.

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