Anticorps Polyclonal de lapin anti-CNNM3

CNNM3 Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF/ICC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13976-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 13976-1-AP (same clone as 13976-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13976-1-AP (CNNM3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13976-1-PBS in a different storage buffer formulation.

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  IP experiment of K-562 using 13976-1-AP (same clone as 13976-1-PBS)

  IP result of anti-CNNM3 (IP:13976-1-AP, 4ug; Detection:13976-1-AP 1:500) with K-562 cells lysate 3600ug. This data was developed using the same antibody clone with 13976-1-PBS in a different storage buffer formulation.

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  IHC staining of human spleen using 13976-1-AP (same clone as 13976-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen using 13976-1-AP (CNNM3 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 13976-1-PBS in a different storage buffer formulation.

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  IHC staining of human spleen using 13976-1-AP (same clone as 13976-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen using 13976-1-AP (CNNM3 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 13976-1-PBS in a different storage buffer formulation.

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  IF Staining of A431 using 13976-1-AP (same clone as 13976-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A431 cells using CNNM3 antibody (13976-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13976-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13976-1-PBS cible CNNM3 dans les applications de WB, IHC, IF/ICC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CNNM3 Protéine recombinante Ag5012
• Nom complet: cyclin M3
• Masse moléculaire calculée: 76 kDa
• Poids moléculaire observé: 85 kDa
• Numéro d’acquisition GenBank: BC037272
• Symbole du gène: CNNM3
• Identification du gène (NCBI): 26505
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Human Cyclin M 3 (CNNM3) has five transmembrane domains located at the N-terminal region and a C terminus containing a CBS pair domain and a cyclin box, both of which are part of the ACD region. CNNM3 magnesium transporter raises the intracellular magnesium content of cancer cells contributing to increased tumor growth and the acquisition of oncogenic properties (PMID: 24632616).

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