Anticorps Recombinant de lapin anti-CNNM4

• Phare
• Validé par KD/KO

CNNM4 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240873E9

N° de cat : 83824-4-PBS

Synonymes

240873E9, ACDP4, Ancient conserved domain-containing protein 4, cyclin M4, Cyclin-M4

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Galerie de données de validation

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  WB analysis of HEK-293 using 83824-4-RR (same clone as 83824-4-PBS)

  WB result of CNNM4 antibody (83824-4-RR; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-CNNM4 transfected HEK-293 cells. This data was developed using the same antibody clone with 83824-4-PBS in a different storage buffer formulation.

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  WB analysis using 83824-4-RR (same clone as 83824-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83824-4-RR (CNNM4 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83824-4-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP00802-3

  Cytometric bead array standard curve of MP00802-3, CNNM4 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83824-4-PBS. Detection antibody: 83824-2-PBS. Standard: Ag5121. Range: 0.313-40 ng/mL.

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  Affinity and Kinetic Characterization of 83824-4-RR

  Biolayer interferometry (BLl) kinetic assays of 83824-4-RR against Human CNNM4 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

83824-4-PBS cible CNNM4 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CNNM4 Protéine recombinante Ag5121
• Nom complet: cyclin M4
• Masse moléculaire calculée: 87 kDa
• Poids moléculaire observé: 90-100 kDa
• Numéro d’acquisition GenBank: BC063295
• Symbole du gène: CNNM4
• Identification du gène (NCBI): 26504
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Ancient conserved domain-containing protein 4/cyclin M4 (CNNM4), a membrane protein that stimulates Mg2+ efflux, binds phosphatase of regenerating liver (PRL), which is frequently overexpressed in malignant human cancers (PMID: 25347473). CNNM4 is predominant in the brain, bone marrow, immune system, and especially abundant in the intestinal tract. CNNM4 localizes at the basolateral membrane of the intestinal epithelia and mediates transcellular Mg2+ transport (PMID: 27006114).

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