Anticorps Recombinant de lapin anti-CNNM4

CNNM4 Recombinant Antibody for IF/ICC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, ELISA

Conjugaison

Non conjugué

CloneNo.

240873C1

N° de cat : 83824-5-PBS

Synonymes

KIAA1592, Cyclin-M4, cyclin M4, Ancient conserved domain-containing protein 4, ACDP4

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Galerie de données de validation

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  IF Staining of LNCaP using 83824-5-RR (same clone as 83824-5-PBS)

  Immunofluorescent analysis of (4% PFA) fixed LNCaP cells using CNNM4 antibody (83824-5-RR, Clone: 240873C1 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83824-5-PBS in a different storage buffer formulation.

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  IF Staining of MCF-7 using 83824-5-RR (same clone as 83824-5-PBS)

  Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using CNNM4 antibody (83824-5-RR, Clone: 240873C1 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83824-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83824-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83824-5-RR against Human CNNM4 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

83824-5-PBS cible CNNM4 dans les applications de IF/ICC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CNNM4 Protéine recombinante Ag5121
• Nom complet: cyclin M4
• Masse moléculaire calculée: 87 kDa
• Numéro d’acquisition GenBank: BC063295
• Symbole du gène: CNNM4
• Identification du gène (NCBI): 26504
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Ancient conserved domain-containing protein 4/cyclin M4 (CNNM4), a membrane protein that stimulates Mg2+ efflux, binds phosphatase of regenerating liver (PRL), which is frequently overexpressed in malignant human cancers (PMID: 25347473). CNNM4 is predominant in the brain, bone marrow, immune system, and especially abundant in the intestinal tract. CNNM4 localizes at the basolateral membrane of the intestinal epithelia and mediates transcellular Mg2+ transport (PMID: 27006114).

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