Anticorps Polyclonal de lapin anti-COBLL1

COBLL1 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31191-1-PBS

Synonymes

KIAA0977, Cordon bleu protein like 1, COBLR1, COBL like 1

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Galerie de données de validation

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  WB analysis using 31191-1-AP (same clone as 31191-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31191-1-AP (COBLL1 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31191-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 31191-1-AP (same clone as 31191-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 31191-1-AP (COBLL1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31191-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 31191-1-AP (same clone as 31191-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 31191-1-AP (COBLL1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31191-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 31191-1-AP (same clone as 31191-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 31191-1-AP (COBLL1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31191-1-PBS in a different storage buffer formulation.

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  IF Staining of HaCaT using 31191-1-AP (same clone as 31191-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HaCaT cells using COBLL1 antibody (31191-1-AP) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 31191-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31191-1-PBS cible COBLL1 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: COBLL1 Protéine recombinante Ag34853
• Nom complet: COBL-like 1
• Poids moléculaire observé: 160 kDa
• Numéro d’acquisition GenBank: BC071588
• Symbole du gène: COBLL1
• Identification du gène (NCBI): 22837
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cordon-blue protein-like 1 (COBLL1), a negative regulator of apoptosis, is associated with lower insulin resistance. COBLL1 is involved in the cancer cell morphogenesis to a neuron-like cell shape observed in the CRPC model cells, promoting cell growth and migration (PMID: 29686105, 29686105). COBLL1 is highly expressed in most human tissues including lung, liver, kidney, pancreas, ovary, spinal cord and brain.

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