Anticorps Polyclonal de lapin anti-COG4

COG4 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31539-1-PBS

Synonymes

COD1, COG complex subunit 4

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Galerie de données de validation

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  WB analysis using 31539-1-AP (same clone as 31539-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31539-1-AP (COG4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31539-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 31539-1-AP (same clone as 31539-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31539-1-AP (COG4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31539-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 31539-1-AP (same clone as 31539-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 31539-1-AP (COG4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31539-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31539-1-PBS cible COG4 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: COG4 Protéine recombinante Ag35295
• Nom complet: component of oligomeric golgi complex 4
• Masse moléculaire calculée: 89kDa，785aa
• Poids moléculaire observé: 89 kDa
• Numéro d’acquisition GenBank: NM_001365426.1
• Symbole du gène: COG4
• Identification du gène (NCBI): 25839
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

COG complex subunit 4 is present in high molecular weight complexes that govern membrane movement between the Golgi and ER. Cog4 dependent trafficking and secretion of ECM components are required for protrusion and extension of the epithelial projections of the inner ear (PMID: 30287385). Loss-of-function COG4-mutant cells have impaired glycosylation and reduced COG4 protein levels (PMID: 30290151).

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