Anticorps Polyclonal de lapin anti-Collagen Type IV
Collagen Type IV Polyclonal Antibody for ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain et plus (2)
Applications
WB, IHC, IF, ELISA
Conjugaison
Non conjugué
N° de cat : 19797-1-AP
Synonymes
Galerie de données de validation
Applications testées
Dilution recommandée
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Applications publiées
| WB | See 11 publications below |
| IHC | See 2 publications below |
| IF | See 4 publications below |
Informations sur le produit
19797-1-AP cible Collagen Type IV dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain
| Réactivité | Humain |
| Réactivité citée | rat, Humain, souris |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Polyclonal |
| Type | Anticorps |
| Immunogène | Peptide |
| Nom complet | collagen, type IV, alpha 5 |
| Masse moléculaire calculée | 161 kDa |
| Numéro d’acquisition GenBank | NM_000495 |
| Symbole du gène | COL4A5 |
| Identification du gène (NCBI) | 1287 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par affinité contre l'antigène |
| Tampon de stockage | PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3 |
| Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
COL4A5 belongs to the type IV collagen family. Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Defects in COL4A5 are the cause of Alport syndrome X-linked (APSX). Deletions covering the N-terminal regions of COL4A5 and COL4A6, which are localized in a head-to-head manner, are the cause of diffuse leiomyomatosis with Alport syndrome (DL-ATS)which also known as esophageal and vulval leiomyomatosis with nephropathy or Alport syndrome and diffuse leiomyomatosis (ATS-DL).
Publications
| Species | Application | Title |
|---|---|---|
Biomaterials A novel bioscaffold with naturally-occurring extracellular matrix promotes hepatocyte survival and vessel patency in mouse models of heterologous transplantation. | ||
PLoS Genet Minor Type IV Collagen α5 Chain Promotes Cancer Progression through Discoidin Domain Receptor-1. | ||
FASEB J Drastic induction of MMP-7 by cortisol in the human amnion: implications for membrane rupture at parturition. | ||
Sci Rep Methanol fixed fibroblasts serve as feeder cells to maintain stem cells in the pluripotent state in vitro. | ||
Front Pharmacol Sappanone a prevents diabetic kidney disease by inhibiting kidney inflammation and fibrosis via the NF-κB signaling pathway | ||
Am J Physiol Cell Physiol miR-29c Induction Contributes to Down-Regulation of Vascular Extracellular Matrix Proteins by Glucocorticoids. |
