Anticorps Polyclonal de lapin anti-COL4A6

COL4A6 Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris et plus (1)

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications(8)

N° de cat : 10807-1-AP

Synonymes

Collagen alpha 6(IV) chain, Collagen alpha-6(IV) chain, Collagen Type IV

---

Galerie de données de validation

• 

  WB analysis of SGC-7901 using 10807-1-AP

  SGC-7901 cells were subjected to SDS PAGE followed by western blot with 10807-1-AP (Collagen Type IV antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of A431 using 10807-1-AP

  A431 cells were subjected to SDS PAGE followed by western blot with 10807-1-AP (Collagen Type IV antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

---

Applications publiées

• WB: See 4 publications below
• IHC: See 2 publications below
• IF: See 2 publications below

Informations sur le produit

10807-1-AP cible COL4A6 dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: rat, Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: COL4A6 Protéine recombinante Ag1118
• Nom complet: collagen, type IV, alpha 6
• Masse moléculaire calculée: 1691 aa, 164 kDa
• Numéro d’acquisition GenBank: BC005305
• Symbole du gène: COL4A6
• Identification du gène (NCBI): 1288
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Collagen alpha-6(IV) chain, known as COL4A6, is a member of the collagen family, the major structural component of basement membranes. There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network. COL4A6 forms a triple helical structure with two other alpha-5-chains, which is stabilized by the presence of glycine as every third residue (PMID: 27377778). COL4A6 is located on the X chromosome in a head-to-head manner with COL4A5 closely (PMID: 23714752). COL4A6 is transcribed from two alternative promoters in a tissue-specific fashion. This antibody detected the cleaved fragment of COL4A6 at ~50 kDa (PMID: 7657706)..

Publications

Species	Application	Title
human	WB	Oncogene; Hepatitis B virus X protein promotes the development of liver fibrosis and hepatoma through downregulation of miR-30e targeting P4HA2 mRNA.; Authors - G X Feng
human	IF	Polymers (Basel); The Development of a 3D PET Fibrous Scaffold Modified with an Umbilical Cord dECM for Liver Tissue Engineering; Authors - Yang Li
rat	WB	Toxicol Appl Pharmacol; High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway.; Authors - Yi Cai
human	IHC	J Tissue Eng Regen Med; Topographical and Chemical Inductive Cues Synergistically Enhance the Schwann Cell Differentiation of Aligned Dental Pulp Stem Cell Sheets; Authors - Michelle D Drewry
human	IHC	J Immunol Res; Partial Reconstruction of Uterus Cervix in Rat by Decellularized Human Uterine Cervical Scaffold Combined with Adipose-Derived Stem Cells (ADSCs); Authors - Yuqi Li
mouse	IF	Oral Dis; Artemisinin suppressed tumour growth and induced vascular normalisation in oral squamous cell carcinoma via inhibition of MIF; Authors - Xiang-Hua Yu

{{ptg:RelatedPrimaryAntibodies}}