Anticorps Polyclonal de lapin anti-COPS7B

COPS7B Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32695-1-PBS

Synonymes

COP9 signalosome complex subunit 7b, CSN7B, JAB1-containing signalosome subunit 7b, SGN7b, Signalosome subunit 7b

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Galerie de données de validation

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  WB analysis using 32695-1-AP (same clone as 32695-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32695-1-AP (COPS7B antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32695-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 32695-1-AP (same clone as 32695-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32695-1-AP (COPS7B antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32695-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32695-1-PBS cible COPS7B dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: COPS7B Protéine recombinante Ag38543
• Nom complet: COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis)
• Masse moléculaire calculée: 30 kDa，264 aa
• Poids moléculaire observé: 30 kDa
• Numéro d’acquisition GenBank: NM_022730.3
• Symbole du gène: COPS7B
• Identification du gène (NCBI): 64708
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

COP9 signalosome complex subunit 7b (COPS7B, also known as CSN7B) is a component of the ribo-interactome that interacts with ribosomes to facilitate ribosome biogenesis and mRNA translation initiation (PMID: 27903243). Increased expression of COPS7B mediated by IGF2BP3 elevates the translational efficiency of genes enriched in mRNA translation and ribosome biogenesis pathways, promoting protein synthesis and driving progression in colorectal cancer (PMID: 37560971).

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