Anticorps Polyclonal de lapin anti-COPS8/COP9

COPS8/COP9 Polyclonal Antibody for WB, IHC, IP, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, ELISA

Conjugaison

Non conjugué

N° de cat : 10089-2-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 10089-2-AP (same clone as 10089-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

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  WB analysis of HepG2 using 10089-2-PBS

  HepG2 cells were subjected to SDS PAGE followed by western blot with 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:1200 incubated at room temperature for 1.5 hours.

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  IP experiment of mouse brain using 10089-2-AP (same clone as 10089-2-PBS)

  IP result of anti-COPS8/COP9 (IP:10089-2-AP, 4ug; Detection:10089-2-AP 1:500) with mouse brain tissue lysate 3200 ug. This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 10089-2-AP (same clone as 10089-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 10089-2-AP (same clone as 10089-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 10089-2-AP (same clone as 10089-2-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 10089-2-AP (same clone as 10089-2-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

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  IHC staining of human gliomas using 10089-2-AP (same clone as 10089-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 10089-2-AP (COPS8/COP9 antibody at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

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  IHC staining of human gliomas using 10089-2-AP (same clone as 10089-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 10089-2-AP (COPS8/COP9 antibody at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

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Informations sur le produit

10089-2-PBS cible COPS8/COP9 dans les applications de WB, IHC, IP, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: COPS8/COP9 Protéine recombinante Ag0143
• Nom complet: COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
• Masse moléculaire calculée: 23 kDa
• Poids moléculaire observé: 23 kDa
• Numéro d’acquisition GenBank: BC003090
• Symbole du gène: COPS8
• Identification du gène (NCBI): 10920
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

COPS8 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases.

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