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Anticorps Polyclonal de lapin anti-COQ2

COQ2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30909-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using COQ2 Polyclonal antibody (30909-1-AP)

    WB analysis using 30909-1-AP (same clone as 30909-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30909-1-AP (COQ2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30909-1-PBS in a different storage buffer formulation.

Informations sur le produit

30909-1-PBS cible COQ2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène COQ2 Protéine recombinante Ag29155
Nom complet coenzyme Q2 homolog, prenyltransferase (yeast)
Masse moléculaire calculée 371 aa, 40 kDa
Poids moléculaire observé35 kDa，40 kDa，45 kDa
Numéro d’acquisition GenBankBC008804
Symbole du gène COQ2
Identification du gène (NCBI) 27235
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

COQ2 (coenzyme Q2, polyprenyltransferase), also known as CL640. It is expected to be located in mitochondrion inner membrane. And the protein is highly expressed in skeletal muscle, adrenal glands and the heart. COQ2 is a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. The protein has three isforms, the calculated molecular weight are 35, 40, 45 kDa.

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