Anticorps Polyclonal de lapin anti-COQ6

• Phare
• Validé par KD/KO

COQ6 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12481-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse heart using 12481-1-AP (same clone as 12481-1-PBS)

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 12481-1-AP (COQ6 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

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  WB analysis using 12481-1-AP (same clone as 12481-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12481-1-AP (COQ6 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse ovary using 12481-1-AP (same clone as 12481-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse ovary tissue slide using 12481-1-AP (COQ6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse ovary using 12481-1-AP (same clone as 12481-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse ovary tissue slide using 12481-1-AP (COQ6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

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  IHC staining of human heart using 12481-1-AP (same clone as 12481-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 12481-1-AP (COQ6 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12481-1-PBS cible COQ6 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: COQ6 Protéine recombinante Ag3164
• Nom complet: coenzyme Q6 homolog, monooxygenase (S. cerevisiae)
• Masse moléculaire calculée: 468 aa, 51 kDa
• Poids moléculaire observé: 51 kDa
• Numéro d’acquisition GenBank: BC014181
• Symbole du gène: COQ6
• Identification du gène (NCBI): 51004
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

COQ6(Coenzyme Q10 monooxygenase 6) is also named CGI-10 and belongs to the ubiH/COQ6 family. It is an evolutionarily conserved flavin-dependent monooxygenase required for the biosynthesis of coenzyme Q10 or ubiquinone. It has 3 isoforms with a molecular mass of 51 kDa, 43 kDa and 49 kDa. In the inner ear, Coq6 is expressed in the spiral ganglion, stria vascularis cells, and spiral ligament(PMID:21540551 ). Defects in COQ6 are the cause of coenzyme Q10 deficiency, primary, type 6 (COQ10D6).

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