Anticorps Polyclonal de lapin anti-CORO1B

CORO1B Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31091-1-PBS

Synonymes

Coronin-2, Coronin-1B, CORONIN 2, Coronin 1B

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Galerie de données de validation

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  WB analysis using 31091-1-AP (same clone as 31091-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31091-1-AP (CORO1B antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31091-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 31091-1-AP (same clone as 31091-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 31091-1-AP (CORO1B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31091-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary cancer using 31091-1-AP (same clone as 31091-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 31091-1-AP (CORO1B antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31091-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31091-1-PBS cible CORO1B dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CORO1B Protéine recombinante Ag34813
• Nom complet: coronin, actin binding protein, 1B
• Masse moléculaire calculée: 498 aa, 54 kDa
• Poids moléculaire observé: 68 kDa
• Numéro d’acquisition GenBank: BC006449
• Symbole du gène: CORO1B
• Identification du gène (NCBI): 57175
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CORO1B (Coronin 1B) is an actin-binding protein that controls actin networks at classical lamellipodia (PMID: 32850828). Coro1B localizes to the plasma membrane, regulates lamellipodia formation, and when phosphorylated, it can no longer bind ARP2/3 and inhibit its actin nucleation abilities (PMID: 22619279).

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