• Phare
  • Validé par KD/KO

Anticorps Polyclonal de lapin anti-INTS11

INTS11 Polyclonal Antibody for WB, IF/ICC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IF/ICC, ELISA

Conjugaison

Non conjugué

Publications(1)

N° de cat : 15860-1-AP

Synonymes

INT11, Cleavage and polyadenylation-specific factor 3-like protein, CPSF3L, CPSF3-like protein, EC:3.1.27.-



Applications testées

Résultats positifs en WBtissu de côlon de souris, tissu splénique de souris
Résultats positifs en IF/ICCcellules HepG2

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Immunofluorescence (IF)/ICCIF/ICC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

15860-1-AP cible INTS11 dans les applications de WB, IF/ICC, ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Réactivité citéeHumain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène INTS11 Protéine recombinante Ag8365
Nom complet cleavage and polyadenylation specific factor 3-like
Masse moléculaire calculée 600 aa, 68 kDa
Poids moléculaire observé 68 kDa
Numéro d’acquisition GenBankBC007978
Symbole du gène INT11
Identification du gène (NCBI) 54973
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS with 0.02% sodium azide and 50% glycerol
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Integrator complex subunit 11 (INT11) is a protein that in humans is encoded by the INTS11 gene. INTS11, also known as Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L), contains a metallo-β-lactamase and β-CASP domain that, together, coordinate two zinc ions within the active site to promote its RNA endonuclease activity. INTS11 is the catalytic subunit of the Integrator (INT) complex, which is crucial for the biogenesis of small nuclear RNAs and enhancer RNAs. INT11 has 5 isoforms with the molecular mass of 56 and 65-68 kDa (PMID: 34516911, PMID: 37054711).

Protocole

Product Specific Protocols
WB protocol for INTS11 antibody 15860-1-APDownload protocol
IF protocol for INTS11 antibody 15860-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Open Med (Wars)

Comprehensive landscape of integrator complex subunits and their association with prognosis and tumor microenvironment in gastric cancer

Authors - Xiaoxia Tong
  • KD Validated

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

Britt (Verified Customer) (05-03-2023)

Antibody works well and is specific to target. Got a nice clear band.

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:1000
  • Cell Tissue Type: HuH7
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