Anticorps Recombinant de lapin anti-CRLF2

CRLF2 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

243090E1

N° de cat : 98415-1-PBS

Synonymes

CRL2, CRLF2Y, IL XR, ILXR, TSLP receptor

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Galerie de données de validation

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  FC experiment of human monocyte-derived mature dendritic cells using 98415-1-RR (same clone as 98415-1-PBS)

  1x10^6 human monocyte-derived mature dendritic cells were surface stained with 0.25 ug Anti-Human CRLF2 Rabbit RecAb (98415-1-RR, Clone: 243090E1) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98415-1-PBS in a different storage buffer formulation.

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  FC experiment of Transfected CHO using 98415-1-RR (same clone as 98415-1-PBS)

  1x10^6 CHO cells or CRLF2-transfected CHO cells were surface stained with 0.25 ug Anti-Human CRLF2 Rabbit RecAb (98415-1-RR, Clone: 243090E1) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98415-1-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected CHO using 98415-1-RR (same clone as 98415-1-PBS)

  1x10^6 CHO cells or CRLF2-transfected CHO cells were surface stained with 0.25 ug Anti-Human CRLF2 Rabbit RecAb (98415-1-RR, Clone: 243090E1) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98415-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98415-1-PBS cible CRLF2 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CRLF2 Protéine recombinante Eg2626
• Nom complet: cytokine receptor-like factor 2
• Masse moléculaire calculée: 42 kDa
• Numéro d’acquisition GenBank: NM_022148.3
• Symbole du gène: CRLF2
• Identification du gène (NCBI): 64109
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Cytokine receptor-like factor 2 (CRLF2), also known as the thymic stromal derived lymphopoietin receptor (TSLPR), which in combination with the interleukin 7 receptor a chain (IL-7R) forms the receptor for thymic stromal lymphopoietin. CRLF2 is a type I cytokine receptor. CRLF2 rearrangements occur either as a translocation to the immunoglobulin heavy-chain enhancer region (IGH-CRLF2) or by a deletion of upstream PAR1 that leads to joining of CRLF2 to adjacent P2RY8. CRLF2 is expressed in heart, skeletal muscle, kidney and adult and fetal liver and is primarily expressed in dendrites and monocytes. (PMID: 20807819; 31644323; 33485429)

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