Anticorps Polyclonal de lapin anti-CRLF3

CRLF3 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11567-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 11567-1-AP (same clone as 11567-1-PBS)

  U-251 cells were subjected to SDS PAGE followed by western blot with 11567-1-AP (CRLF3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11567-1-PBS in a different storage buffer formulation.

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Informations sur le produit

11567-1-PBS cible CRLF3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CRLF3 Protéine recombinante Ag2144
• Nom complet: cytokine receptor-like factor 3
• Masse moléculaire calculée: 442 aa, 50 kDa
• Poids moléculaire observé: 51 kDa
• Numéro d’acquisition GenBank: BC023567
• Symbole du gène: CRLF3
• Identification du gène (NCBI): 51379
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cytokine receptor-like factor 3 (CRLF3), a member of the group 1 in the prototypic class I cytokine receptors, contains the conserved cytokine receptor motif WSXWS, a single transmembrane segment and an intracellular Janus kinase (JAK) docking site (PMID: 31680856). CRLF3 is expressed in most normal human tissues and many tumor cell lines and has been reported to negatively regulate cell cycle progression (PMID: 19427400). CRLF3 has been identified as a human neuroprotective EV-3 (Epo) receptor (PMID: 37168680). It is involved neurogenesis, neuron survival, and dendritic development (PMID: 34233200).

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