Anticorps Monoclonal anti-CRTAC1

CRTAC1 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain, Lapin, porc, rat, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2A11E2

N° de cat : 68276-1-PBS

Synonymes

ASPIC, ASPIC1, cartilage acidic protein 1, CEP 68, CEP68, CRTAC1, FLJ10320

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Galerie de données de validation

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  WB analysis using 68276-1-Ig (same clone as 68276-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68276-1-Ig (CRTAC1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68276-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 68276-1-Ig (same clone as 68276-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using CRTAC1 antibody (68276-1-Ig, Clone: 2A11E2 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 68276-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68276-1-PBS cible CRTAC1 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, Lapin, porc, rat, souris

• Réactivité: Humain, Lapin, porc, rat, souris
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: CRTAC1 Protéine recombinante Ag32813
• Nom complet: cartilage acidic protein 1
• Masse moléculaire calculée: 661 aa, 71 kDa
• Poids moléculaire observé: 71 kDa
• Numéro d’acquisition GenBank: BC034245
• Symbole du gène: CRTAC1
• Identification du gène (NCBI): 55118
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CRTAC1 (cartilage acidic protein 1) is also named as ASPIC1 and CEP68. CRTAC1 is an extracellular matrix protein of human chondrogenic tissue. CRTAC1 promotes cell proliferation, migration and extracellular matrix regeneration and remodeling in primary human fibroblasts (PMID:32084494). CRTAC1 expression is decreased in tissue samples of bladder urothelial carcinoma (PMID:34818994). CRTAC1 overexpression promotes the pyroptosis of human lens epithelial cells by facilitating the reactive oxygen species (ROS) production in the formation of cataract (PMID:32838966). CRTAC1 was the most compelling and robust biomarker for osteoarthritis severity and progression (PMID:35924962).

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