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Anticorps Polyclonal de lapin anti-CRTAM/CD355

CRTAM/CD355 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32680-1-PBS

Synonymes

CD355, Class-I MHC-restricted T-cell-associated molecule, Crtam, Cytotoxic and regulatory T-cell molecule

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using CRTAM/CD355 Polyclonal antibody (32680-1-AP)

    WB analysis using 32680-1-AP (same clone as 32680-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32680-1-AP (CRTAM/CD355 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32680-1-PBS in a different storage buffer formulation.

Informations sur le produit

32680-1-PBS cible CRTAM/CD355 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

Réactivité rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène Protéine recombinante
Nom complet cytotoxic and regulatory T cell molecule
Masse moléculaire calculée44 kDa
Poids moléculaire observé70 kDa
Numéro d’acquisition GenBankNM_001281954.1
Symbole du gène Crtam
Identification du gène (NCBI) 54698
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cytotoxic and regulatory T cell molecule (CRTAM, also known as CD355) is an immunoglobulin-superfamily transmembrane protein with V and C1-like Ig domains, which is involved in epithelial cell adhesion (PMID: 18329370; 20556794). CRTAM is critical to instruct the differentiation of CD4+ cytotoxic T cells (CTL) through the induction of eomesodermin and CTL-related genes (PMID: 26694968). It also regulates CD8+ T cell retention within the lymph node and eventually effector function (PMID: 19752223). The predicted molecular weight of CRTAM is 44 kDa. Due to glycosylation, the observed molecular weight of CRTAM can be apparent at ~80 kDa (PMID: 16300832).

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