Anticorps Recombinant de lapin anti-CRTAM/CD355

CRTAM/CD355 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250055A1

N° de cat : 98420-3-PBS

Synonymes

CD355, Class-I MHC-restricted T-cell-associated molecule, Crtam, Cytotoxic and regulatory T-cell molecule

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 98420-3-RR (same clone as 98420-3-PBS)

  1x10^6 untreated or anti-CD3/CD28 treated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CRTAM/CD355 Rabbit RecAb (98420-3-RR, Clone: 250055A1) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse CD8a (53-6.7) (APC-65069, Clone: 53-6.7). Cells were not fixed. This data was developed using the same antibody clone with 98420-3-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse splenocytes using 98420-3-RR (same clone as 98420-3-PBS)

  1x10^6 anti-CD3/CD28 treated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CRTAM/CD355 Rabbit RecAb (98420-3-RR, Clone: 250055A1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). 1x10^6 untreated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse Crtam(CD355 ) Rabbit RecAb (98420-3-RR, Clone:250055A1) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (black, dashed). Cells were not fixed. This data was developed using the same antibody clone with 98420-3-PBS in a different storage buffer formulation.

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Informations sur le produit

98420-3-PBS cible CRTAM/CD355 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CRTAM/CD355 Protéine recombinante Eg2691
• Nom complet: cytotoxic and regulatory T cell molecule
• Masse moléculaire calculée: 44 kDa
• Numéro d’acquisition GenBank: NM_001281954.1
• Symbole du gène: Crtam
• Identification du gène (NCBI): 54698
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Cytotoxic and regulatory T cell molecule (CRTAM, also known as CD355) is an immunoglobulin-superfamily transmembrane protein with V and C1-like Ig domains, which is involved in epithelial cell adhesion (PMID: 18329370; 20556794). CRTAM is critical to instruct the differentiation of CD4+ cytotoxic T cells (CTL) through the induction of eomesodermin and CTL-related genes (PMID: 26694968). It also regulates CD8+ T cell retention within the lymph node and eventually effector function (PMID: 19752223).

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