Anticorps Monoclonal anti-CRX

CRX Monoclonal Antibody for WB, IHC, Cytometric bead array, Indirect ELISA, Sample test

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc, rat, souris

Applications

WB, IHC, Cytometric bead array, Indirect ELISA, Sample test

Conjugaison

Non conjugué

CloneNo.

1C3C11

N° de cat : 67555-1-PBS

Synonymes

1C3C11, cone rod homeobox, Cone-rod homeobox protein, CORD2, CRD

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Galerie de données de validation

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  WB analysis using 67555-1-Ig (same clone as 67555-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67555-1-Ig (CRX antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67555-1-PBS in a different storage buffer formulation.

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  WB analysis of Y79 using 67555-1-Ig (same clone as 67555-1-PBS)

  Y79 cells were subjected to SDS PAGE followed by western blot with 67555-1-Ig (CRX antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67555-1-PBS in a different storage buffer formulation.

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  Sample test of MP51402-2

  Sample test of MP51402-2, CRX Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67555-1-PBS. Detection antibody: 67555-4-PBS.

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  IHC staining of mouse eye using 67555-1-Ig (same clone as 67555-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse eye tissue slide using 67555-1-Ig (CRX antibody) at dilution of 1:4000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67555-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP51402-2

  Cytometric bead array standard curve of MP51402-2, CRX Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67555-1-PBS. Detection antibody: 67555-4-PBS. Standard:Ag30086. Range: 0.098-100 ng/mL.

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Informations sur le produit

67555-1-PBS cible CRX dans les applications de WB, IHC, Cytometric bead array, Indirect ELISA, Sample test et montre une réactivité avec des échantillons Humain, porc, rat, souris

• Réactivité: Humain, porc, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: CRX Protéine recombinante Ag30086
• Nom complet: cone-rod homeobox
• Masse moléculaire calculée: 299 aa, 32 kDa
• Poids moléculaire observé: 37 kDa
• Numéro d’acquisition GenBank: BC016664
• Symbole du gène: CRX
• Identification du gène (NCBI): 1406
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cone-rod homeobox (Crx) is a homeodomain transcription factor and member of the Otx family, which has been thought to play a critical role in determining and maintaining the phenotype of both pinealocytes and retinal photoreceptors [PMID:17467693]. In the mammalian retina, Crx plays an essential role in the normal development and maintenance of cones and rods and regulates expression of the network of genes that characterize the retina [PMID:17653270]. Elimination of Crx by disruption of the homeobox domain results in loss of the image-forming visual system but not the non-image-forming visual system controlling circadian rhythms [PMID:20438719].

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