Anticorps Recombinant de lapin anti-Cryptochrome 1

Cryptochrome 1 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

240520B12

N° de cat : 83602-5-PBS

Synonymes

CRY1, Cryptochrome-1, CRY 1, 240520B12

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Galerie de données de validation

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  WB analysis using 83602-5-RR (same clone as 83602-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83602-5-RR (CRY1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83602-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83602-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83602-5-RR against Human Cryptochrome 1 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

83602-5-PBS cible Cryptochrome 1 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Cryptochrome 1 Protéine recombinante Ag4270
• Nom complet: cryptochrome 1 (photolyase-like)
• Masse moléculaire calculée: 586 aa, 66 kDa
• Poids moléculaire observé: 60-66 kDa
• Numéro d’acquisition GenBank: BC030519
• Symbole du gène: CRY1
• Identification du gène (NCBI): 1407
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cryptochrome circadian clock 1 (CRY1) is a flavin adenine dinucleotide-binding protein with MW of 66 kDa. CRY1 is a key component of the circadian core oscillator complex, which regulates the circadian clock. CRY1 predominantly displays evening-time expression and serves as a strong repressor of morning-time elements (E box/E-prime box) when bound to the BMAL1 (ARNTL; 602550)/CLOCK (601851) complex (PubMed: 21236481).

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