Anticorps Recombinant de lapin anti-CSF1R/CD115

CSF1R/CD115 Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241675D4

N° de cat : 84477-6-PBS

Synonymes

CSF1R, CSF-1 receptor, CSF 1 R, CD115, C FMS

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Galerie de données de validation

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  WB analysis using 84477-6-RR (same clone as 84477-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84477-6-RR (CSF1R antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84477-6-PBS in a different storage buffer formulation.

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  IF Staining of THP-1 using 84477-6-RR (same clone as 84477-6-PBS)

  Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using CSF1R antibody (84477-6-RR, Clone: 241675D4 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84477-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84477-6-RR

  Biolayer interferometry (BLl) kinetic assays of 84477-6-RR against Human CSF1R were performed. The affinity constant is 0.775 nM.

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Informations sur le produit

84477-6-PBS cible CSF1R/CD115 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: colony stimulating factor 1 receptor
• Masse moléculaire calculée: 972 aa, 108 kDa
• Poids moléculaire observé: 160 kDa
• Numéro d’acquisition GenBank: BC047521
• Symbole du gène: CSF1R/CD115
• Identification du gène (NCBI): 1436
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CSF1R (colony-stimulating factor 1 receptor) belongs to the type III protein tyrosine kinase receptor family. CSF1R-mediated signaling is crucial for the differentiation and survival of the mononuclear phagocyte system and macrophages in particular (PMID: 28716061).

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