Anticorps Recombinant de lapin anti-CSF1R/CD115

CSF1R/CD115 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242213B1

N° de cat : 98334-2-PBS

Synonymes

Csf1r, 242213B1, CD115, CSF 1R, CSF-1 receptor

---

Galerie de données de validation

• 

  FC experiment of mouse peritoneal macrophages using 98334-2-RR (same clone as 98334-2-PBS)

  1x10^6 mouse peritoneal macrophages were surface stained with 0.25 ug Anti-Mouse CSF1R/CD115 Rabbit RecAb (98334-2-RR, Clone: 242213B1) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Mouse CD11b (M1/70) (APC-65055, Clone: M1/70). Cells were not fixed. This data was developed using the same antibody clone with 98334-2-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse peritoneal macrophages using 98334-2-RR (same clone as 98334-2-PBS)

  1x10^6 mouse peritoneal macrophages were surface stained with 0.25 ug Anti-Mouse CSF1R/CD115 Rabbit RecAb (98334-2-RR, Clone: 242213B1) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98334-2-PBS in a different storage buffer formulation.

---

Informations sur le produit

98334-2-PBS cible CSF1R/CD115 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CSF1R/CD115 Protéine recombinante Eg1816
• Nom complet: colony stimulating factor 1 receptor
• Masse moléculaire calculée: 109 kDa
• Numéro d’acquisition GenBank: NM_001037859.2
• Symbole du gène: CSF1R/CD115
• Identification du gène (NCBI): 12978
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

The CSF-1 receptor (CSF1R), also called CD115, is activated by the homodimeric growth factors colony-stimulating factor-1 (CSF-1) and interleukin-34 (IL-34). It plays important roles in development and in innate immunity by regulating the development of most tissue macrophages and osteoclasts, of Langerhans cells of the skin, of Paneth cells of the small intestine, and of brain microglia. It also regulates the differentiation of neural progenitor cells and controls functions of oocytes and trophoblastic cells in the female reproductive tract. Owing to this broad tissue expression pattern, it plays a central role in neoplastic, inflammatory, and neurological diseases.

{{ptg:RelatedPrimaryAntibodies}}