Anticorps Polyclonal de lapin anti-CSPG4

CSPG4 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31623-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 31623-1-AP (same clone as 31623-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31623-1-AP (CSPG4 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31623-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31623-1-PBS cible CSPG4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: chondroitin sulfate proteoglycan 4
• Masse moléculaire calculée: 251kd
• Poids moléculaire observé: 250-300 kDa
• Numéro d’acquisition GenBank: NM_001897.5
• Symbole du gène: CSPG4
• Identification du gène (NCBI): 1464
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CSPG4 is a proteoglycan that plays a role in cell proliferation and migration, stimulates endothelial cell motility during microvascular morphogenesis and may also inhibit neurite outgrowth and growth cone collapse during axon regeneration. CSPG4 is expressed on more than 90% of human melanoma tissues and cultured cells. It is a target of specific diagnosis and immunotherapy with antiidiotypic antibodies due, in part, to its roles in growth control, adhesion, cell-substratum interactions, and cell-cell contacts (PMID: 10587647; 11278606).

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