Anticorps Polyclonal de lapin anti-CT55

CT55 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32040-1-PBS

Synonymes

Cancer/testis antigen 55, CXorf48, Tumor antigen BJ-HCC-20

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Galerie de données de validation

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  WB analysis using 32040-1-AP (same clone as 32040-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32040-1-AP (CXorf48 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32040-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32040-1-PBS cible CT55 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CT55 Protéine recombinante Ag36155
• Nom complet: chromosome X open reading frame 48
• Poids moléculaire observé: 30 kDa
• Numéro d’acquisition GenBank: BC020662
• Symbole du gène: CXorf48
• Identification du gène (NCBI): 54967
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The Cancer/Testis Antigen (CTA) genes comprise a group of genes whose expression under physiological conditions is restricted to the testis but is activated in many human cancers. CT55 is a new autophagic manipulator to regulate spermatogenesis via selectively interacting with LAMP2 and GABARAP (which are key regulators in the autophagy process) and further fine-tuning their expression. Cancer-testis antigen 55 (CT55) mutation induced male infertility with extreme disruption in sperm production, morphology, and locomotion (PubMed:36481789).

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