Anticorps Recombinant de lapin anti-CTLA-4/CD152

CTLA-4/CD152 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

APC Fluorescent Dye

CloneNo.

241100B8

N° de cat : APC-FcA98147

Synonymes

Ctla4, Cd152, Ctla 4, Ly 56

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Galerie de données de validation

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  FC experiment of mouse splenocytes using APC-FcA98147

  1x10^6 untreated or Con A-treated mouse splenocytes were surface stained with PE Anti-Mouse CD4 (RM4-4) and 0.1 ug APC Anti-Mouse CTLA-4/CD152 Rabbit RecAb (APC-FcA98147, Clone: 241100B8). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using APC-FcA98147

  1x10^6 Con A-treated mouse splenocytes were surface stained with 0.1 ug APC Anti-Mouse CTLA-4/CD152 Rabbit RecAb (APC-FcA98147, Clone: 241100B8) (red) or 0.1 ug APC Rabbit IgG Isotype Control RecAb (APC-FcA98136, Clone: 240953C9) (blue). 1x10^6 untreated mouse splenocytes were surface stained with 0.1 ug APC Anti-Mouse CTLA-4/CD152 Rabbit RecAb (APC-FcA98147, Clone:241100B8) (black, dashed). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: Con A treated mouse splenocytes,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

APC-FcA98147 cible CTLA-4/CD152 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CTLA-4/CD152 Protéine recombinante Eg0632
• Nom complet: cytotoxic T-lymphocyte-associated protein 4
• Masse moléculaire calculée: 25 kDa
• Numéro d’acquisition GenBank: NM_009843.4
• Symbole du gène: CTLA-4
• Identification du gène (NCBI): 12477
• Conjugaison: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CTLA-4, also known as CD152, belonging to the immunoglobulin superfamily, is primarily found on activated T cells and regulatory T cells (Tregs). CTLA-4 is closely related to the T-cell costimulatory CD28, and both molecules bind to B7-1 and B7-2 on antigen-presenting cells. CTLA-4 acts as a negative regulatory molecule of T-cell responses. Besides the full-length transmembrane form, CTLA-4 also exists in a truncated soluble form (sCTLA-4).

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