Anticorps Polyclonal de lapin anti-CTTNBP2

CTTNBP2 Polyclonal Antibody for WB, IHC, IP, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IF, IP, ELISA

Conjugaison

Non conjugué

Publications(4)

N° de cat : 17893-1-AP

Synonymes

C7orf8, Cortactin-binding protein 2, CortBP2, KIAA1758, Orf4

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Galerie de données de validation

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  WB analysis of mouse brain using 17893-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 17893-1-AP (CTTNBP2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse kidney using 17893-1-AP

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 17893-1-AP (CTTNBP2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

• 

  IP experiment of mouse brain using 17893-1-AP

  IP result of anti-CTTNBP2 (IP:17893-1-AP, 5ug; Detection:17893-1-AP 1:500) with mouse brain tissue lysate 4000ug.

• 

  IHC staining of human testis using 17893-1-AP

  Immunohistochemical analysis of paraffin-embedded human testis using 17893-1-AP (CTTNBP2 antibody) at dilution of 1:100 (under 10x lens).

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  IHC staining of human testis using 17893-1-AP

  Immunohistochemical analysis of paraffin-embedded human testis using 17893-1-AP (CTTNBP2 antibody) at dilution of 1:100 (under 40x lens).

• 

  IHC staining of human brain using 17893-1-AP

  Immunohistochemical analysis of paraffin-embedded human brain using 17893-1-AP (CTTNBP2 antibody) at dilution of 1:100 (under 10x lens).

• 

  IHC staining of human brain using 17893-1-AP

  Immunohistochemical analysis of paraffin-embedded human brain using 17893-1-AP (CTTNBP2 antibody) at dilution of 1:100 (under 40x lens).

• 

  IHC staining of human spleen using 17893-1-AP

  Immunohistochemical analysis of paraffin-embedded human spleen using 17893-1-AP (CTTNBP2 antibody) at dilution of 1:100 (under 10x lens).

• 

  IHC staining of human spleen using 17893-1-AP

  Immunohistochemical analysis of paraffin-embedded human spleen using 17893-1-AP (CTTNBP2 antibody) at dilution of 1:100 (under 40x lens).

• 

  IHC staining of human lung using 17893-1-AP

  Immunohistochemical analysis of paraffin-embedded human lung using 17893-1-AP (CTTNBP2 antibody) at dilution of 1:100 (under 10x lens).

• 

  IHC staining of human lung using 17893-1-AP

  Immunohistochemical analysis of paraffin-embedded human lung using 17893-1-AP (CTTNBP2 antibody) at dilution of 1:100 (under 40x lens).

• 

  IHC staining of human kidney using 17893-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney using 17893-1-AP (CTTNBP2 antibody) at dilution of 1:100 (under 10x lens).

• 

  IHC staining of human kidney using 17893-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney using 17893-1-AP (CTTNBP2 antibody) at dilution of 1:100 (under 40x lens).

• 

  IHC staining of human placenta using 17893-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta using 17893-1-AP (CTTNBP2 antibody) at dilution of 1:100 (under 10x lens).

• 

  IHC staining of human placenta using 17893-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta using 17893-1-AP (CTTNBP2 antibody) at dilution of 1:100 (under 40x lens).

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Applications testées

• Résultats positifs en WB: tissu cérébral de souris, tissu rénal de souris
• Résultats positifs en IP: tissu cérébral de souris
• Résultats positifs en IHC: tissu testiculaire humain, tissu cérébral humain, tissu placentaire humain, tissu pulmonaire humain, tissu rénal humain, tissu splénique humain; il est suggéré de démasquer l'antigène avec un tampon de TE buffer pH 9.0; (*) À défaut, 'le démasquage de l'antigène peut être 'effectué avec un tampon citrate pH 6,0.

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2000
• Immunoprécipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
• Immunohistochimie (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 1 publications below
• IHC: See 1 publications below
• IF: See 2 publications below

Informations sur le produit

17893-1-AP cible CTTNBP2 dans les applications de WB, IHC, IF, IP, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CTTNBP2 Protéine recombinante Ag12219
• Nom complet: cortactin binding protein 2
• Masse moléculaire calculée: 1663 aa, 181 kDa
• Poids moléculaire observé: 181 kDa
• Numéro d’acquisition GenBank: BC106000
• Symbole du gène: CTTNBP2
• Identification du gène (NCBI): 83992
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Cortactin Binding Protein 2 (CTTNBP2) is a cytoskeleton regulator predominantly expressed in neurons and highly enriched at dendritic spines. CTTNBP2 controls the synaptic expression of a set of zinc-regulated autism-associated genes and influences NMDAR function and signaling (PMID: 32492416).

Publications

Species	Application	Title
mouse	WB	Nat Neurosci; Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition.; Authors - Luye Qin
human	IF	Dev Cell; Single-cell MultiOmics and spatial transcriptomics demonstrate neuroblastoma developmental plasticity; Authors - Yunyun Xu
human	IHC	Mod Pathol; Expression profiling of small intestinal neuroendocrine tumors identifies subgroups with clinical relevance, prognostic markers and therapeutic targets.; Authors - Ellinor Andersson
human	IF	Sci Adv; Maintaining hypoxia environment of subchondral bone alleviates osteoarthritis progression; Authors - Hao Zhang

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