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Anticorps Recombinant de lapin anti-CXCL1

CXCL1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240990E4

N° de cat : 83937-3-PBS

Synonymes

GRO-alpha(5-73), GRO-alpha(4-73), CXCL 1, C-X-C motif chemokine 1, C X C motif chemokine 1

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of HUVEC cells using CXCL1 Recombinant antibody (83937-3-RR)

    WB analysis of HUVEC using 83937-3-RR (same clone as 83937-3-PBS)

    Untreated, LPS and Brefeldin A treated HUVEC cells were subjected to SDS PAGE followed by western blot with 83937-3-RR (CXCL1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83937-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83937-3-RR

    Affinity and Kinetic Characterization of 83937-3-RR

    Biolayer interferometry (BLl) kinetic assays of 83937-3-RR against Human CXCL1 were performed. The affinity constant is below 1 pM.

Informations sur le produit

83937-3-PBS cible CXCL1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène CXCL1 Protéine recombinante Ag2917
Nom complet chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
Masse moléculaire calculée 8 kDa to 14 kDa
Poids moléculaire observé11 kDa
Numéro d’acquisition GenBankBC011976
Symbole du gène CXCL1
Identification du gène (NCBI) 2919
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CXCL1 a is a member of CXC family and also known as keratinocyte-derived chemokines (KC) or growth-related oncogene (GRO). CXCL1 is expressed by macrophages, neutrophils and epithelial cells. CXCL1 binding specifically to the CXC chemokine receptor CXCR2, is involved in fibrogenesis and angiogenesis. This protein also plays a role in inflammation and as a chemoattractant for neutrophils. CXCL1 is upregulated in some types of human cancer, including colorectal, bladder, breast, prostate and skin cancers.

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