Anticorps Recombinant de lapin anti-CXCL1

CXCL1 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

240990E4

N° de cat : 83937-3-RR

Synonymes

GRO-alpha(5-73), GRO-alpha(4-73), CXCL 1, C-X-C motif chemokine 1, C X C motif chemokine 1

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Galerie de données de validation

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  WB analysis of HUVEC using 83937-3-RR

  Untreated, LPS and Brefeldin A treated HUVEC cells were subjected to SDS PAGE followed by western blot with 83937-3-RR (CXCL1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 83937-3-RR

  Biolayer interferometry (BLl) kinetic assays of 83937-3-RR against Human CXCL1 were performed. The affinity constant is below 1 pM.

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Applications testées

• Résultats positifs en WB: cellules HUVEC,

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

83937-3-RR cible CXCL1 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CXCL1 Protéine recombinante Ag2917
• Nom complet: chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
• Masse moléculaire calculée: 8 kDa to 14 kDa
• Poids moléculaire observé: 11 kDa
• Numéro d’acquisition GenBank: BC011976
• Symbole du gène: CXCL1
• Identification du gène (NCBI): 2919
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

CXCL1 a is a member of CXC family and also known as keratinocyte-derived chemokines (KC) or growth-related oncogene (GRO). CXCL1 is expressed by macrophages, neutrophils and epithelial cells. CXCL1 binding specifically to the CXC chemokine receptor CXCR2, is involved in fibrogenesis and angiogenesis. This protein also plays a role in inflammation and as a chemoattractant for neutrophils. CXCL1 is upregulated in some types of human cancer, including colorectal, bladder, breast, prostate and skin cancers.

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