Anticorps Monoclonal anti-CXCL16

• Phare
• Validé par KD/KO

CXCL16 Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, souris

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2H7B3

N° de cat : 60123-1-PBS

Synonymes

Small-inducible cytokine B16, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, CXCL 16, C-X-C motif chemokine 16, C X C motif chemokine 16

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Galerie de données de validation

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  WB analysis using 60123-1-Ig (same clone as 60123-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60123-1-Ig (CXCL16 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60123-1-PBS in a different storage buffer formulation.

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  WB analysis of SH-SY5Y using 60123-1-Ig (same clone as 60123-1-PBS)

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 60123-1-Ig (CXCL16 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60123-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP51127-1

  Cytometric bead array standard curve of MP51127-1, CXCL16 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60123-2-PBS. Detection antibody: 60123-1-PBS. Standard:Ag4883. Range: 0.391-100 ng/mL.

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Informations sur le produit

60123-1-PBS cible CXCL16 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: CXCL16 Protéine recombinante Ag4883
• Nom complet: chemokine (C-X-C motif) ligand 16
• Masse moléculaire calculée: 273 aa, 30 kDa
• Poids moléculaire observé: 35 kDa, 60 kDa
• Numéro d’acquisition GenBank: BC017588
• Symbole du gène: CXCL16
• Identification du gène (NCBI): 58191
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CXCL16 is a recently discovered cytokine belonging to the CXC chemokine family, which is synthesised in plasmacytoid dendritic cell as a transmembrane molecule. It exists in a transmembrane and soluble form. The transmembrane form of CXCL16 functions as an adhesion molecule for CXCR6-expressing cells, whereas the soluble form of CXCL16 mediates infiltration of circulating cells into sites of injury. CXCL16, has been proposed as an important pathogenic mediator in inflammatory diseases, including rheumatoid arthritis, glomerulonephritis, or prostate cancer. CXCL16 has been implicated in some forms of renal disease such as lupus nephritis and antiglomerular basement membrane nephritis. CXCL16 also plays a pivotal role in the pathogenesis of angiotensin II-induced renal injury and fibrosis through regulation of macrophage and T cell infiltration and bone marrow-derived fibroblast accumulation.

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