Anticorps Recombinant de lapin anti-CXCL16

CXCL16 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242984H8

N° de cat : 85680-4-PBS

Synonymes

C X C motif chemokine 16, C-X-C motif chemokine 16, CXCL 16, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, Small-inducible cytokine B16

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Galerie de données de validation

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  WB analysis of human testis using 85680-4-RR (same clone as 85680-4-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 85680-4-RR (CXCL16 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85680-4-PBS in a different storage buffer formulation.

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Informations sur le produit

85680-4-PBS cible CXCL16 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: chemokine (C-X-C motif) ligand 16
• Masse moléculaire calculée: 273 aa, 30 kDa
• Poids moléculaire observé: 28-30 kDa
• Numéro d’acquisition GenBank: BC017588
• Symbole du gène: CXCL16
• Identification du gène (NCBI): 58191
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CXCL16 is a recently discovered cytokine belonging to the CXC chemokine family, which is synthesised in plasmacytoid dendritic cell as a transmembrane molecule. It exists in a transmembrane and soluble form. The transmembrane form of CXCL16 functions as an adhesion molecule for CXCR6-expressing cells, whereas the soluble form of CXCL16 mediates infiltration of circulating cells into sites of injury. CXCL16, has been proposed as an important pathogenic mediator in inflammatory diseases, including rheumatoid arthritis, glomerulonephritis, or prostate cancer. CXCL16 has been implicated in some forms of renal disease such as lupus nephritis and antiglomerular basement membrane nephritis. CXCL16 also plays a pivotal role in the pathogenesis of angiotensin II-induced renal injury and fibrosis through regulation of macrophage and T cell infiltration and bone marrow-derived fibroblast accumulation.

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